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5 Οκτ 2017 · The interpretation of a testosterone level found to be low on a sample taken at 09.00, requires a serum prolactin, LH and FSH measurement in order to rule out secondary hypogonadism. Also, sex hormone binding globulin (SHBG) measurement may help.
In patients with signs and symptoms indicative of hypogonadism, determining luteinizing hormone (LH) and follicle-stimulating hormone (FSH) levels together with the initial testosterone level is usually most efficient.
Elevated LH and FSH values indicate primary (testicular) hypogonadism, whereas low or importantly even inappropriately ‘normal’ LH and FSH values may indicate secondary (pituitary–hypothalamic) hypogonadism.
central GnRH pulses, consistently raised LH and FSH levels reliably identify gonadal insufficiency even under less-stringent sampling conditions. Late onset hypogonadism
Younger age (40-49 years, OR = 8.14 [1.35-49.13]) and nonsmoking (OR = 5.39 [1.48-19.65]) predicted recovery from HLH. Men with iHLH developed erectile dysfunction, poor health, cardiovascular disease (CVD) and cancer more frequently than pNLH men.
FSH levels can be detected using a simple blood test. Normal FSH levels in adult males are typically between 1.5 to 12.4 mIU/mL. However, what counts as a normal value may vary from lab to lab, as some labs have different testing standards.
Serum FSH and LH levels are usually ≤ 5 mIU/mL (5 IU/L) before puberty and between 5 and 15 mIU/mL (5 and 15 IU/L) in adulthood. Semen analysis should be done in all men who are seeking fertility treatment.
