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  1. 3 Αυγ 2023 · Initial dose: 5 mg/kg IM or IV infusion (over 30 to 120 minutes) per day, given in divided doses 3 to 4 times a day Maintenance dose: 3 mg/kg IM or IV infusion (over 30 to 120 minutes) per day, given in divided doses 3 to 4 times a day

  2. Use the Interval Calculator to determine the timing of subsequent doses after a gentamicin level has been measured. A gentamicin level should always be taken after the first dose. Levels must be taken 6 – 14 hours post dose. In stable renal function, if course length is > 3 days, levels can be taken twice weekly. Dose Calculator.

  3. Once-daily dosing for gentamicin is recommended for most patients, except in endocarditis, where lower, multiple daily dosing is used. Once daily doses: The gentamicin dosing calculator on the GAPP app should be used to calculate the gentamicin dose.

  4. An antimicrobial app and/or online calculator is available and should be used to calculate the initial gentamicin dose. STEP 1: . Calculate, prescribe and administer the first dose. To reduce the risk of mortality, commence gentamicin administration within 1 hour of recognising sepsis.

  5. Creatinine (micromol/L) Gentamicin dose calculator for adults aged 16 and over. Take sample 6-14 hours after the first dose then refer to the gentamicin plot. Seek advice from infection specialist if gentamicin is required beyond 3-4 days.

  6. Adults: The recommended dosage of gentamicin sulfate for patients with serious infections and normal renal function is 3 mg/kg/day, administered in three equal doses every eight hours . For patients with life-threatening infections, dosages up to 5 mg/kg/day may be administered in three or four equal doses.

  7. Step 1: Calculate, prescribe and administer the first dose. To reduce the risk of mortality, commence gentamicin administration within 1 hour of recognising sepsis. If creatinine is known – use the online Gentamicin calculator (preferred method) or the guidelines in Table 1 (below).

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