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This study investigated, whether gut microbiota composition is altered in Gilbert’s Syndrome (GS), a mild form of chronically elevated serum unconjugated bilirubin (UCB) compared to matched controls. Potential differences in the incidence of CRC-associated bacterial species in GS were also assessed.
Gilbert’s syndrome manifests as mild unconjugated asymptomatic hyperbilirubinaemia, usually found in young adults during routine laboratory check-ups or after an intercurrent illness. The diagnosis is typically made per exclusionem, i.e. by excluding other causes of hyperbilirubinaemia.
5 Οκτ 2024 · Gilbert Syndrome. Lafaine M. Grant; Thomas W. Faust; Viveksandeep Thoguluva Chandrasekar; Savio John. Author Information and Affiliations. Last Update: October 5, 2024. Go to: Objectives: Identify the clinical signs and triggers of mild unconjugated hyperbilirubinemia in patients with Gilbert syndrome.
1 Οκτ 2023 · Due to the potent antioxidant and hormone-like effects of bilirubin, individuals with Gilbert's syndrome are protected from the “diseases of civilisation” such as cardiovascular diseases, certain cancers, and autoimmune or neurodegenerative diseases.
23 Οκτ 2023 · Gilbert syndrome is an inherited disorder of the liver that results in an overabundance of a substance known as bilirubin. While some people with Gilbert syndrome develop yellowing of the skin or eyes, most people have no symptoms at all.
Gilbert’s syndrome (GS) is the commonest hereditary unconjugated hyperbilirubinaemia. GS is a benign, self-resolving jaundice with otherwise normal liver function tests and absence of haemolysis. GS can coexist with other causes of unconjugated hyperbilirubinaemia, in particular hereditary spherocytosis/ thalassaemia.
6 Σεπ 2022 · Gilbert syndrome (GS) is a genetic syndrome of mild unconjugated hyperbilirubinaemia, by definition <102 micromol/L (<6 mg/dL) (rarely exceeding 68.4 micromol/L [4 mg/dL]). The liver function is otherwise normal. Common syndrome affecting approximately 6% of the general population.
