Αποτελέσματα Αναζήτησης
27 Σεπ 2017 · A series of 105 GBM patients treated with 35 Gy in 10 fractions had a median survival, from salvage HFSRT, of 11 months, without clinically significant acute morbidity and only one case of late grade 3CNS toxicity (78). However, no direct comparison between salvage SRS and HFSRT is available.
The standard treatment for GBMs is surgical resection followed by chemoradiotherapy. The robust DNA repair and self-renewing capabilities of glioblastoma cells and glioma initiating cells (GICs), respectively, promote resistance against all current treatment modalities.
13 Ιαν 2023 · Glioblastoma, thus, remains a significant unmet clinical need with dismal survival and limited effective treatment options. There is an urgent need for innovative, safe, and effective therapies for these uniformly fatal neoplasms.
15 Απρ 2022 · Here, we set forth the rationales for these promising therapies in treating GBM, review the potential novel agents, the current status of preclinical and clinical trials, and discuss the challenges and future perspectives in glioblastoma immuno-oncology.
6 Μαΐ 2024 · GBM's gold-standard treatment comprises surgical resection followed by adjuvant radiochemotherapy. Clarifying patients' goals of care is essential as soon as the diagnosis is made, given the poor prognosis even with complete treatment.
31 Δεκ 2021 · Glioblastoma (GBM) is the most common aggressive malignant tumor in brain neuroepithelial tumors and remains incurable. A variety of treatment options are currently being explored to improve patient survival, including small molecule inhibitors, viral therapies, cancer vaccines, and monoclonal antibodies.
15 Οκτ 2024 · Glioblastoma (GBM) is an aggressive and lethal type of brain tumor in human adults. The standard of care offers minimal clinical benefit, and most GBM patients experience tumor recurrence...
