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For a complete marrow evaluation (CME), testing should include a CBC, bone marrow aspirate, and bone marrow biopsy. A CBC gives excellent quantitative and morphologic information; it should be collected at the same time or within 24 hours of the bone marrow aspirate.
- Laboratory Evaluation of Bone Marrow - StatPearls - NCBI Bookshelf
A comprehensive laboratory bone marrow examination includes...
- Laboratory Evaluation of Bone Marrow - StatPearls - NCBI Bookshelf
The bone marrow examination is an essential investigation for the diagnosis and management of many disorders of the blood and bone marrow. The aspirate and trephine biopsy specimens are complemen-tary and when both are obtained, they provide a comprehensive evaluation of the bone marrow.
Evaluation of the hematopoietic system should be performed using a multi-pronged approach (i.e., peripheral blood exam including a CBC and differential, bone marrow smear exam or total femur counts and evaluation of cytocentrifuge preparations and/or bone marrow histopathology).
30 Οκτ 2023 · This article will review the embryology of the bone marrow as well as its histology. Additionally, the constituent cell lineages and their function will be discussed, together with clinically relevant processes and pathologies.
15 Μαΐ 2015 · Bone marrow (BM) tissue biopsy evaluation, including trephine biopsy and clot section, is an integral part of BM investigation and is often followed by ancillary studies, in particular immunohistochemistry (IHC). IHC provides in situ coupling of morphological assessment and immunophenotype.
3 Μαρ 2024 · A comprehensive laboratory bone marrow examination includes a complete blood count (CBC) and analysis of the peripheral blood smear (PBS), bone marrow aspirate, core biopsy specimen, clot section, and cytometric flow.
7 Φεβ 2011 · Histological evaluation alone will provide an assessment of overall hematopoietic cellularity, can identify subtle focal or multifocal lesions not easily identified by smear evaluation (i.e., necrosis or inflammation), and may allow for a general estimation of the proportion and maturation of granulocytic and erythroid cells, as well as megakary...
