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  1. 10 Δεκ 2021 · The pain of alcohol is indicated in the collection of papers in this special issue: ethanol in alcoholic beverages is toxic to human health, causing 7.1% of all deaths amongst those aged less than 70 years (two million deaths a year), with the three top causes of death being cirrhosis of the liver, road injuries, and tuberculosis [1].

  2. Alcohol’s Effects on the Liver, the Neuroendocrine System, and Bone. The medical consequences of chronic alcohol abuse and dependence have been well documented in adults. They include liver disease, lung disease, compromised immune function, endocrine disorders, and brain changes.

  3. There is a large body of evidence showing that alcohol can modify gene expression through epigenetic processes, namely DNA methylation and nucleosomal remodeling via histone modifications. In that regard, chronic exposure to ethanol modifies DNA and histone methylation, histone acetylation, and microRNA expression.

  4. Abstract. Studies have focused on the effects of chronic alcohol consumption and the mechanisms of tissue injury underlying alcoholic hepatitis and cirrhosis, with less focus on the pathophysiological consequences of binge alcohol consumption. Alcohol binge drinking prevalence continues to rise, particularly among individuals ages 18 to 24.

  5. 28 Ιουν 2024 · Overview. Alcohol and alcoholic beverages contain ethanol, which is a psychoactive and toxic substance with dependence-producing properties. Alcohol has been widely used in many cultures for centuries, but it is associated with significant health risks and harms.

  6. 25 Μαρ 2022 · This article reviews the impact of alcohol use on different systems and organs, summarizing available evidence regarding its medical implications. It examines current basic and clinical data regarding mechanisms to highlight factors and processes that may be targetable to improve patient outcomes.

  7. More recent research highlights the relationships between health and behavioral, psychological, and social variables. In the early years of scientific medicine, most clinicians and researchers thought only in terms of single causes: specific agents that cause specific disease.

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