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Pain is a subjective experience with two complementary aspects: one is a localized sensation in a particular body part; the other is an unpleasant quality of varying severity commonly associated with behaviors directed at relieving or terminating the experience.
24 Ιουλ 2023 · Nociceptive signal transduction to the brain is what elicits the perception of pain. The complex biopsychosocial phenomenon of pain occurs in the cortical and subcortical regions, such as the thalamus, amygdala, hypothalamus, periaqueductal grey, basal ganglia and areas of the cerebral cortex.
28 Σεπ 2015 · This article describes how that “pain message” is transmitted to the spinal cord and the brain and how the brain responds to the stimulus, while identifying pain relief strategies linked to the physiological process.
Pain is transmitted by primary afferents, which have their cell bodies in the dorsal root ganglion (DRG). They terminate in the dorsal horn of the spinal cord. The dorsal horn cells are divided into specific regions or laminae called Rexed’s laminae with lamina I being the most superficial. 9
24 Ιουλ 2018 · Pain has been considered as a concept of sensation that we feel as a reaction to the stimulus of our surrounding, putting us in harm’s way and acting as a form of defense mechanism that our...
1 Οκτ 2022 · The experience of pain is a complex balance between nociception, the neural pathways transmitting noxious stimulus to the brain, signalling systems, modulation from higher centres and the unique perception of the individual.
Pain transmission can be inter-rupted in the periphery by giving drugs that block sensitization of nociceptors (NSAIDs) or by blocking nerve transmission (lidocaine injection into a peripheral nerve). Pain per-ception can also be altered by giving drugs that work in the CNS (opioids).
