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9 Ιουν 2023 · Despite extensive research, technical development and clinical experimentation, no current surgery-based, material-based, cell-based or drug-based treatment can reliably restore the structure and...
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Metrics - Failure of cartilage regeneration: emerging...
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1 Δεκ 2013 · The ideal treatment would reestablish the low friction properties of cartilage with the ability to resist wear over time by repopulating a lesion with chondrocytes able to produce a hyaline matrix that is fully integrated with surrounding host cartilage.
23 Σεπ 2014 · Treating cartilage defects with autologous chondrocytes delivered with a hyaluronic-acid-based scaffold has shown promise.
16 Δεκ 2021 · Preventing hyaline cartilage fibrosis and promoting the hyalinization of fibrocartilage may provide new therapeutic ideas for repairing cartilage damage (Shi and Li, 2021). There are two strategies that could be employed to prevent hyaline cartilage fibrosis.
And it was the right kind of cartilage: hyaline. Within weeks, the treated defects showed a remarkable improvement, especially compared to the controls. A similar treatment might be even more effective in humans.
17 Οκτ 2022 · Hyaline cartilage is the most copious type of cartilage in the human body. [1] . It is pale blue-white and smooth to the touch. It is primarily composed of type II collagen and proteoglycans. The surface is usually moist, but the cartilage becomes dry, thinner, and more yellow with age.
22 Δεκ 2022 · A novel strategy for the repair of articular cartilage involves converting fibrocartilage to hyaline cartilage by modifying the cytoskeleton of fibrotic chondrocytes.