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Genital herpes, mainly caused by infection with herpes simplex virus (HSV) -2, and sometimes by HSV-1, affects more than 500 million people worldwide. Infection often occurs without or with only mild symptoms and remains unrecognized, which further facilitates transmission.
14 Δεκ 2023 · In a study of lab-engineered cells, Harvard Med researchers identify how the immune system neutralizes the herpesvirus. The research maps, for the first time, the maneuvers used by virus and host in the cell nucleus, a poorly understood terrain of host-pathogen interaction.
12 Ιουλ 2024 · This article looks at the causes and symptoms of genital herpes and explains how this common viral disease is diagnosed and treated. It also offers tips on when to seek treatment to potentially reduce the duration and severity of an outbreak, or to suppress and prevent outbreaks and transmission.
18 Αυγ 2021 · In this review, we will examine how interferons are induced and their critical role in how they shape the local immune response to HSV-2 infection in the FRT.
Lymphadenopathy, fever and cervicitis (in women)/proctitis (in men) are relatively common associated symptoms. Genital herpes may manifest atypically, particularly in the female genital tract, making the clinical diagnosis far more difficult.
6 Μαρ 2013 · The rapid clearance of HSV-2 in the genital mucosa by resident and virus-specific immune cells that persist in the mucosa suggests new ways to harness the immune system to develop effective...
Most people with herpes have no symptoms or only mild symptoms. Many people aren’t aware they have the infection and can pass along the virus to others without knowing. Symptoms can include painful, recurring blisters or ulcers. New infections may cause fever, body aches and swollen lymph nodes.