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23 Ιουν 2011 · CVD is the leading cause of death worldwide; preventive approaches can have major public health implications. An increased dietary intake of n–3 fatty acids is one such approach. This review...
- NEJM
ALTHOUGH earlier studies 1 2 3 suggested that dietary fish...
- NEJM
15 Απρ 2003 · Alarge body of data points to potential benefits of N-3 polyunsaturated fatty acids in reducing the risk of cardiovascular disease (CVD). 1 Available data suggest that higher intakes of N-3 fatty acids will reduce various forms of CVD, especially sudden cardiovascular death.
26 Ιουλ 2012 · In this double-blind study with a 2-by-2 factorial design, we randomly assigned 12,536 patients who were at high risk for cardiovascular events and had impaired fasting glucose, impaired...
17 Οκτ 2017 · Because of their long hydrocarbon chain, EPA, DPA and DHA are sometimes termed very long-chain n-3 fatty acids, in order to differentiate them from the 18-carbon plant-derived n-3 fatty acids like α-linolenic acid (ALA; 18:3n-3) and stearidonic acid (SDA; 18:4n-3).
EPA and DHA appear to be the most important n-3 fatty acids, but roles for n-3 docosapentaenoic acid are now also emerging. Intakes of EPA and DHA are usually low, typically below those recommended. Increased intakes result in higher concentrations of EPA and DHA in blood lipids, cells and tissues. …
The n-6 PUFA arachidonic acid (AA) is the precursor of prostaglandins, leukotrienes, and related compounds that have important roles in inflammation and in the regulation of immunity. Feeding fish oil results in partial replacement of AA in cell membranes by EPA.
The effects of n-3 fatty acids from fish oils (eicosapentaenoic acid and docosahexaenoic acid) and plant oils (alpha-linolenic acid) on human serum lipids and lipoproteins are reviewed.
