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  1. The initial inflammatory response of infection which normally produces symptoms and signs of sepsis are blunted or may be absent in the elderly, while later presentation may be very severe with very rapid progression to septic shock [13, 21, 26].

  2. 12 Ιουν 2024 · Sepsis should be suspected in an acutely deteriorating patient in whom there is clinical evidence or strong suspicion of infection. Have a low threshold for suspicion. Think ‘Could this be sepsis?’ whenever an acutely unwell person presents with likely infection, even if their temperature is normal. Remember that sepsis represents the ...

  3. 6 Σεπ 2024 · Sepsis syndromes in adults: Epidemiology, definitions, clinical presentation, diagnosis, and prognosis; Society guideline links: Sepsis in children and adults; Stress ulcers in the intensive care unit: Diagnosis, management, and prevention; The decision to intubate; Treatment and prevention of invasive aspergillosis

  4. 28 Μαΐ 2024 · Sepsis and the inflammatory response that ensues can lead to multiple organ dysfunction syndrome and death. The epidemiology, definitions, risk factors, clinical presentation, diagnosis, and outcomes of sepsis are reviewed here.

  5. In adults with sepsis, intravenous low-dose corticosteroids may reduce organ failure at 7 days, and duration of mechanical ventilation, vasopressor therapy, and intensive care stay. However, whether corticosteroids reduce short or longer-term mortality is unclear.

  6. 18 Οκτ 2024 · Prognosis. Guidelines. Images and videos. References. Patient information. Calculators. Evidence. Log in or subscribe to access all of BMJ Best Practice. Last reviewed: 30 Sep 2024. Last updated: 18 Oct 2024. Summary. Sepsis can progress rapidly to multiorgan failure and shock, and is often fatal.

  7. The final model, which exhibited an area under the receiver operating characteristic curve of 0.8 (95% confidence interval (CI) 0.73–0.88), included five factors that could be assessed when antimicrobial susceptibility testing results become available: severe sepsis or shock at presentation, Pitt bacteremia score of at least 6, Charlson ...

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