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26 Δεκ 2019 · Top, the typical nonlinear relation between luminal pressure and area in large elastic arteries, explained by the progressive shift in load bearing from elastin to collagen fibers. Data translate into distensibility and pulse wave velocity (PWV) with the use of the Bramwell-Hill relation.
Large, elastic arteries are composed of cells and a specialized extracellular matrix that provides reversible elasticity and strength. Elastin is the matrix protein responsible for this reversible elasticity that reduces the workload on the heart and dampens pulsatile flow in distal arteries.
2 Μαΐ 2005 · The goal of this preventive strategy is to improve the precision for early detection and treatment by identifying a marker or markers for early cardiovascular disease that could serve as a surrogate for disease progression, morbid events, and the response to therapy.
1 Φεβ 2002 · A simplified model of arterial elasticity has been used in many studies in which measurements are confined to the circumferential direction, and elastic non‐linearity is treated by defining incremental elastic properties over a limited region of the stress strain curve that is taken to be linear (for instance, that corresponding to the part ...
4 Μαΐ 2021 · An arterial wall has both elastic and viscous characteristics, and pathological and degenerative changes in the wall tissue affect the viscoelastic behavior of the artery wall. The arterial viscoelasticity may provide useful information regarding the development and progression of arterial diseases.
1 Μαΐ 2013 · The first techniques, developed to evaluate arterial stiffness, use indirect measurements such as pulse wave velocity or the analysis of variations in intra-arterial pressure and volume to estimate arterial stiffness.
Reduced arterial elasticity causes elevated blood pressure and reduced pulse dampening, which places undue strain on the heart and downstream target organs. Arterial elasticity is conferred by elastic fibers whose elastic properties come from cross-linked elastin.