Αποτελέσματα Αναζήτησης
30 Οκτ 2023 · This tissue is known as bone marrow and is responsible for the production of blood cells – a process known as hematopoiesis. This article will review the embryology of the bone marrow as well as its histology.
23 Δεκ 2011 · This Review describes the dynamic interactions that occur between haematopoietic stem cells (HSCs), immune cells and their specialized niches in the bone marrow.
13 Ιαν 2017 · Bone marrow (BM) is a source of hematopoietic stem cells (HSCs). HSCs are localized in both the endosteum, in the so-called endosteal niche, and close to thin-walled and fenestrated sinusoidal vessel in the center of BM, in the so-called vascular niche.
15 Ιαν 2014 · Postnatally, the bone marrow is the primary site of HSC maintenance and haematopoiesis, but in response to haematopoietic stress the niche can shift to extramedullary sites.
27 Ιουλ 2021 · The Notch signaling pathway is required for the emergence of the definitive Hematopoietic Stem Cell (HSC) during embryonic development, but its role in BM HSC homeostasis is convoluted. Recent work has begun to explore novel roles for the Notch signaling pathway in downstream progenitor populations.
1 Μαρ 2022 · Abstract. Angiogenesis, hematopoiesis and osteogenesis are fundamental processes mediating complex and essential biological functions. In the bone marrow, endothelial cells (ECs) are a principal mediator of regulatory signals that govern hematopoietic and mesenchymal stem cells.
26 Νοε 2015 · The bone marrow niche is a unique microenvironment that integrates the physiology of the skeleton and the marrow to maintain the haematopoietic stem cell pool and support whole-organism...
