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Pocket Guide for asthma management and prevention for adults and children older than 5 years (updated 2020). Summary for primary health care providers, to be used in conjunction with the main GINA report. Difficult-to-treat and severe asthma in adolescent and adult patients. Diagnosis and Management.
GINA now recommends that all adults and adolescents with asthma should receive either symptom-driven (in mild asthma) or daily low dose ICS-containing controller treatment, to reduce their risk of serious exacerbations.
Intermittent ICS dosing includes courses of ICS treatment used for brief periods, usually in response to symptoms or as an add-on with or without a long-acting beta 2-agonist (LABA). Recommendations for ICS treatment are organized by age. Children Ages 0–4 Years with Recurrent Wheezing . KEY POINT.
The intensity of treatment depends on the severity of symptoms: up to 3 treatments at 20-minute intervals as needed. In steps 3 and 4, the preferred option includes the use of ICS-formoterol 1 to 2 pufs as needed up to a maximum total daily maintenance and rescue dose of 12 pufs (54 mcg). .
The IMPACT randomized placebo-controlled trial compared three treatment strategies in 225 adults with mild persistent asthma: daily low dose ICS (budesonide 200 mcg twice daily), zafirlukast 20 mg twice daily, and intermittent ICS (budesonide 800 mcg for 10 days if symptoms “worsened” according to a symptom-based action plan (i.e. yellow ...
Both the 2020 NAEPP Asthma Update and the 2021 GINA report recommend prescribing SMART for adults and adolescents with low-dose maintenance ICS-formoterol in step 3 and medium-dose maintenance ICS-formoterol in step 4. 1, 2 Formulations of ICS-formoterol and recommended dose ranges of low and medium ICS doses vary among countries ...
15 Ιαν 2019 · Dosing was not standardized, but most studies used weight-based dosing according to guidelines from the British National Formulary for Children, which advises 40 mg per kg of body weight, up to...
