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When exposed to mechanical impact, a biological system such as the human skin, brain, or liver is rapidly accelerated, which could result in blunt injuries. for this reason, an acceleration...
1 Νοε 2015 · Mechanobiology: A field at the interface of biology, physics, and bioengineering, which focuses on how cell/tissue mechanics and physical forces influence cell behavior, cell and tissue morphogenesis, and diseases related to these processes.
This review clarifies how mechanical properties of the ECM or of a biomaterial can influence stem cells fate, which is the final effect of step-by-step sequence having the first sign in the determination of the cells’ shape.
18 Νοε 2014 · Biological mechano-transduction and force-dependent changes scale from protein conformation (â„« to nm) to cell organization and multi-cell function (mm to cm) to affect cell organization, fate, and homeostasis.
8 Νοε 2017 · In this Review, we provide an overview of the types of mechanical cues that affect stem cells and of biomaterial-based systems that can be used to control and manipulate these cues.
Mechanobiology is the study of how biological components such as cells, tissues, and organs can sense and respond to mechanical cues to regulate numerous biological processes, including development, differentiation, physiology, and diseases [1, 2, 3].
Mechanical stimulation affects growth and differentiation of stem cells. This may be used to guide lineage-specific cell fate decisions and therefore opens fascinating opportunities for stem cell biology and regenerative medicine.
