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  1. 6 Απρ 2020 · Human episodic memory critically depends on subregions of the medial temporal lobe, which are part of functional brain systems such as the anterior-temporal and the posterior-medial system. Here we analysed how Alzheimer’s pathology affects functional connectivity within these systems.

  2. 1 Οκτ 2013 · This article discusses recent findings dealing with recognition memory and a long lasting involvement of the hippocampus and perirhinal cortex in episodic memory, based on functional imaging and lesion studies.

  3. 9 Οκτ 2016 · Recent fMRI data in MCI and AD are beginning to reveal relationships between abnormalities of functional activity in the MTL memory system and in functionally connected brain regions, such as the precuneus.

  4. Atrophy of the medial temporal lobe (MTL) is a biological characteristic of Alzheimer’s disease (AD) and can be measured by segmentation of magnetic resonance images (MRI). ... axonal degeneration and synaptic loss, ... Early stages of tau pathology and its associations with functional connectivity, atrophy and memory. Brain 144, 2771–2783 ...

  5. 28 Απρ 2016 · It is widely assumed that incipient protein pathology in the medial temporal lobe instigates the loss of episodic memory in Alzheimer’s disease, one of the earliest cognitive deficits in this type of dementia. Within this region, the hippocampus is seen as the most vital for episodic memory.

  6. 1 Αυγ 2003 · Whereas the medial temporal lobe has traditionally been associated with the encoding, storage and retrieval of long-term memories, the prefrontal cortex has been linked with cognitive control...

  7. It is widely assumed that incipient protein pathology in the medial temporal lobe instigates the loss of episodic memory in Alzheimer's disease, one of the earliest cognitive deficits in this type of dementia. Within this region, the hippocampus is seen as the most vital for episodic memory.

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