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Meclofenamic Acid in Animals. Meclofenamic acid is a fenemate (anthranilic acid) NSAID available for horses as a granular preparation and for dogs as an oral tablet. The recommended dosage in horses is 2.2 mg/kg per day for 5–7 days; the recommended dosage in dogs is 1.1 mg/kg per day for 5–7 days.
This summary contains important information about NSAIDs (Including but not limited to: aspirin, carprofen (Rimadyl, Novox), deracoxib (Deramaxx), firocoxib (Previcox, Equioxx), meloxicam (Metacam), piroxicam (Feldene) or robenacoxib (Onsior).
Table 1. Characteristics of an Ideal NSAID for Use in Cats. 1. Spares COX-1 and targets COX-2. 2. Provides targeted action. Prolonged action in targeted tissues. Appropriate duration of action in the central nervous system. Spares ‘non target’ tissues. 3. Can be administered with ease and accuracy.
NSAIDs have been available to treat dogs with degenerative joint disease (DJD),17 only a restricted range has been licensed for short-term (up to a few days) use in cats. At the time of writing, at least one NSAID – meloxicam – has been licensed for long-term use in cats in many regions of the world, transforming our
1 Απρ 2009 · NSAIDS with data addressing use specifically in cats include piroxicam, ketoprofen and carprofen. Tepoxalin (Zubrin®), the newest NSAID approved for use in dogs, is a "dual inhibitor", targeting both COX and LOX, thus targeting prostaglandins and leukotrienes.
1 Ιουλ 2007 · Currently, several NSAIDs (aspirin, carprofen, cinchophen, deracoxib, etodolac, firocoxib, flunixin, ketoprofen, meloxicam, phenylbutazone, tepoxalin, tolfenamic acid and vedaprofen) have approval for the control of canine perioperative and/or chronic pain in various countries.
Dogs: 1–2 mg/kg, PO or SC, every 24 h. Cats: 2 mg/kg, SC, every 24 h for 3 days; or 1 mg/kg, PO, every 24 h. aIf no dosage is listed for cats, the drug is not recommended for use in that species. In these topics. Pain Management in Small Animals with Lameness.
