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Objective: To evaluate the results of a brief course of testosterone therapy in boys with delayed puberty and to compare the responses seen in boys with constitutional delayed puberty (CDP), boys with obesity, and boys with possible gonadotropin deficiency.
25 Νοε 2022 · Constitutional delay of growth and puberty (CDGP) is the most common reason for delayed puberty in healthy male adolescents. The main indication for medical treatment for this condition is psychosocial burden.
3 Ιαν 2019 · The treatment of constitutional delay of growth and puberty (CDGP) is an underinvestigated area in adolescent medicine. We tested the hypothesis that peroral aromatase inhibition with letrozole is more efficacious than intramuscular injection of low-dose testosterone in inducing puberty in boys with CDGP.
Degree of activation of the pituitary-testicular axis in early pubertal boys with constitutional delay of growth and puberty determines the growth response to treatment with testosterone or oxandrolone.
30 Οκτ 2020 · Testosterone (T) therapy is routinely prescribed in adolescent males with constitutional delay of growth and puberty (CDGP) or hypogonadism. T plays a critical role in male sexual development and function, beginning in utero and continuing through infancy, adolescence, and beyond [ 1 ].
7 Μαρ 2017 · Constitutional delay of growth and puberty (CDGP) is a disorder occurring in healthy adolescents and is characterised by slowing of the childhood growth phase, delay in bone maturation and delayed pubertal growth spurt. CDGP is more common in boys than in girls (1).
19 Φεβ 2024 · Letrozole versus testosterone for promotion of endogenous puberty in boys with constitutional delay of growth and puberty: a randomised controlled phase 3 trial.