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Pregnancy Category: C. Lactation Category: S • There are no indications for methylergonovine during a continuing pregnancy. • While oxytocin remains the drug of choice to prevent and treat postpartum uterine atony, methylergonovine rapidly treats most women should oxytocin fail.
28 Απρ 2018 · Methergine is commonly used more broadly for bleeding not only associated with pregnancy, delivery, or pregnancy loss or fetal demise, but in a variety of other medical situations most likely to prevent excessive bleeding and the associated symptomatology associated with anemia. METHODS:
4 Απρ 2024 · Advice and warnings for the use of Methylergonovine (Methergine) during pregnancy. FDA Pregnancy Category C - Risk cannot be ruled out.
17 Νοε 2014 · Women at risk for abnormal placentation and subsequent hemorrhage (such as those with a history of cesarean delivery and placenta previa) are discussed specifically in all 4 guidelines. RANZOG and SOGC guidelines recommend antenatal assessment of placentation and location in these high-risk women to prompt transfer to a tertiary care center or ...
Oral methylergometrine maleate (0.5 mL PO, q.8 h) has been proposed as an adjuvant therapy in cases of moderate uterine hemorrhage, for example after parturition. In women, it displays a uterotonic effect, probably via a stimulation of myometrial α-adrenergic receptors. Its action remains effective for 4–6 h.
10 Φεβ 2020 · Methylergonovine is intended for use after delivery of the anterior shoulder, after delivery of the placenta, or during the puerperium; use is contraindicated during pregnancy. Methylergonovine is recommended when a supplemental uterotonic agent is needed; due to maternal side effects it is not preferred for initial use (ACOG 183 2017).
30 Απρ 2022 · According to current evidence, oxytocin therapy combined with other uterotonics (carbetocin, methylergonovine, ergometrine, misoprostol, prostaglandin analogs, and TXA) is more beneficial than oxytocin therapy alone for the prevention of PPH, but this merits additional research.
