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  1. pubs.rsna.org › doi › 10Use of Methotrexate in Gynecologic and Obstetric Practice: What...

    1 Οκτ 2021 · The patient presented with abdominal pain, fever, and vaginal bleeding and had elevated liver function test results and white blood cell count. Gray-scale (A) and color Doppler (B) transvaginal US images show heterogeneous material at the site of the collapsed CSEP with no significant blood flow.

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      Methotrexate (MTX) is the primary pharmaceutical agent that...

  2. academic.oup.com › qjmed › articleThe effects of methotrexate on pregnancy, fertility and lactation

    1 Οκτ 1999 · With the increasing use of MTX in the rheumatic diseases and other inflammatory conditions, it is essential that all cases of MTX exposure in pregnancy are reported to central surveillance bodies to provide a complete picture of the teratogenicity of MTX.

  3. www.ncbi.nlm.nih.gov › pmc › articlesMethotrexate in pregnancy: still many unanswered questions

    15 Μαρ 2023 · In addition to the approved indications for the drug treatment of malignancies and inflammatory disorders, it is used for the non-surgical treatment of ectopic pregnancy and elective termination of pregnancy (TOP). The dose differs according to indication and also plays a role in teratology.

  4. www.medicalnewstoday.com › articles › 325549Methotrexate and pregnancy: Effects and how to stay safe

    24 Μαρ 2022 · Methotrexate is not suitable for use during pregnancy, due to a risk of birth abnormalities. Both partners should avoid methotrexate when planning to become pregnant and during...

  5. www.ncbi.nlm.nih.gov › books › NBK582834Methotrexate - Mother To Baby | Fact Sheets - NCBI Bookshelf

    Methotrexate was used to induce abortions and is currently used to treat ectopic pregnancies (pregnancies that grow outside the uterus). Some brand names for methotrexate are: Otrexup®, Trexall®, Rheumatrex®, and Rasuvo®.

  6. rmdopen.bmj.com › content › 9Methotrexate in pregnancy: still many unanswered questions

    Methotrexate (MTX) is a folate antagonist with known teratogenicity including abortifacient effects that interfere with DNA synthesis. We want to discuss on which findings teratogenicity is based and which open questions still exist.

  7. www.drugs.com › pregnancy › methotrexateMethotrexate Use During Pregnancy | Drugs.com

    8 Μαΐ 2023 · Advice and warnings for the use of Methotrexate during pregnancy. FDA Pregnancy Category X - Not for use in pregnancy