Αποτελέσματα Αναζήτησης
Η τιμολόλη (timolol) είναι βήτα-1 και βήτα-2 (μη-εκλεκτικός) αναστολέας αδρενεργικών υποδοχέων που δεν έχει σημαντική ενδογενή συμπαθομιμητική δράση, άμεση κατασταλτική δράση στο μυοκάρδιο ή σταθεροποιητική δράση στη μεμβράνη. Η τιμολόλη μειώνει την ενδοφθάλμια πίεση μειώνοντας τον σχηματισμό υδατοειδούς στο κροσσωτό επιθήλιο.
This combination medication is used to treat high pressure inside the eye due to glaucoma (open-angle type) or other eye diseases (such as ocular hypertension). Lowering high pressure inside the...
3 Φεβ 2011 · The novel fixed combination of latanoprost 0.005% and timolol 0.5% has been studied extensively, and overall this medication has proved effective in controlling symptoms and has become a viable option for the treatment of glaucoma.
13 Νοε 2024 · Brimonidine tartrate/timolol maleate ophthalmic solution 0.2%/0.5% is an alpha-adrenergic receptor agonist with a beta-adrenergic receptor inhibitor indicated for the reduction of elevated intraocular pressure (IOP) in patients with glaucoma or ocular hypertension who require adjunctive or replacement therapy due to inadequately controlled IOP ...
1 Δεκ 2022 · The concentrations of brimonidine and timolol in the vitreous humor and aqueous humor were significantly positively correlated (P < 0.0001, R 2 = 0.97; and P < 0.0001, R 2 = 0.96, respectively). These data suggest that the penetration of brimonidine into ocular tissues is similar to that of timolol.
The ocular hypotensive efficacy and safety of brimonidine tartrate 0.2%, a highly selective alpha 2-adrenergic agonist, was compared with that of timolol 0.5%, a nonselective beta-blocker in two multicenter, randomized, double-masked studies.
Methods: To measure the main treatment effects of a fixed combination of brimonidine 0.2%-timolol 0.5%, we conducted three small studies: (1) a comparison of diurnal intraocular pressure (IOP) at baseline and at 6 months after brimonidine/timolol fixed-combination therapy (n = 81); (2) an assessment of the effects of one drop of the brimonidine ...