Αποτελέσματα Αναζήτησης
11 Ιαν 2024 · Gene vaccines work by harnessing advances in biochemistry, molecular biology, genetics and chemistry to deliver selected portions of the deoxyribonucleic acid (DNA), or messenger ribonucleic acid (mRNA), of the pathogen of interest.
1 Ιουλ 2024 · A direct comparison between the trials of DNA and mRNA vaccines clearly points out that mRNA is currently more favorable than DNA – almost all nucleic acid vaccine trials that are in phase 3 are based on mRNA instead of DNA, which indicates better results from earlier phase mRNA trials.
4 Οκτ 2024 · mRNA vaccines are newcomers in the field of vaccinology. Decades of work have now addressed fundamental hurdles of in vitro-transcribed (IVT) mRNA, including its highly inflammatory nature and...
23 Δεκ 2020 · RNA vaccines encode the antigen of interest in messenger RNA (mRNA) or self-amplifying RNA (saRNA) – molecular templates used by cellular factories to produce proteins. Because of its transitory nature, there is zero risk of it integrating with our own genetic material.
12 Ιαν 2018 · mRNA vaccines have elicited potent immunity against infectious disease targets in animal models of influenza virus, Zika virus, rabies virus and others, especially in recent years, using...
DNA and messenger RNA (mRNA) vaccines do not require the use of a live infectious agent such as a bacteria or virus, have been shown to stimulate disease-fighting responses in T-cells and B-cells, and are more stable, less costly and easier to produce in mass quantities than traditional vaccines.
25 Αυγ 2021 · Clinically used synthetic mRNA is transcribed in vitro from a DNA plasmid by using the bacteriophage RNA polymerase T7 (T3 and SP6 polymerases can also be used).
