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  1. 11 Ιαν 2024 · Gene vaccines work by harnessing advances in biochemistry, molecular biology, genetics and chemistry to deliver selected portions of the deoxyribonucleic acid (DNA), or messenger ribonucleic acid (mRNA), of the pathogen of interest.

  2. 4 Οκτ 2024 · A deeper understanding of the mechanisms of action of mRNA vaccines, application of novel technologies enabling rational antigen design, and innovative vaccine delivery strategies and...

  3. 25 Αυγ 2021 · This study reports the synthesis of SM-102 (Lipid 8); the ionizable lipid used in Moderna’s SARS-CoV-2 vaccine candidate mRNA-1273.

  4. 1 Ιουλ 2024 · Nucleic acid technology has revolutionized vaccine development, enabling rapid design and production of RNA and DNA vaccines for prevention and treatment of diseases. The successful deployment of mRNA and plasmid DNA vaccines against COVID-19 has further validated the technology.

  5. 23 Δεκ 2020 · RNA vaccines encode the antigen of interest in messenger RNA (mRNA) or self-amplifying RNA (saRNA) – molecular templates used by cellular factories to produce proteins. Because of its transitory nature, there is zero risk of it integrating with our own genetic material.

  6. Vaccines for SARS-CoV-2 deliver antigens in three main forms: inactive whole virus, antigen proteins, and genetic instructions (mRNA or DNA). How does a vaccine help prevent disease? Why don’t vaccines cause the same symptoms as the virus? Why do you think vaccine developers might select one vaccine type over another?

  7. 12 Ιουν 2024 · In this review article, we focus mainly on mRNA, recent advances in its stability when used as a vaccine, and technologies adopted to produce mRNA vaccines, for example, SARS-CoV-2 or COVID-19 vaccines.