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1 Δεκ 2022 · The article highlights the story of neuroscientist John Sinclair and his discovery that prescribing naltrexone 1 hour before drinking improves drinking outcomes by decreasing the reward of and cravings for alcohol, which may be especially helpful for binge drinkers.
1 Ιαν 2001 · Abstract. — Eight double-blind placebo-controlled clinical trials in five countries have demonstrated the safety and efficacy of naltrexone as an adjunct in alcoholism treatment. The efficacy depends, however, on how naltrexone is used.
13 Δεκ 2001 · Although naltrexone, an opiate-receptor antagonist, has been approved by the Food and Drug Administration for the treatment of alcohol dependence, its efficacy is uncertain.
Although debates over the efficacy of oral naltrexone and acamprosate in treating alcohol use disorders tend to focus on their global efficacy relative to placebo or their efficacy relative to each other, the underlying reality may be more nuanced.
Prevalence of naltrexone treatment prescribed in alcohol use disorder (AUD) admissions from 2000–2018 by frequency of alcohol use at admission using TEDS-A data. Temporal trends were significant by the Cochran–Armitage trend test ( p < 0.0001).
14 Αυγ 2008 · Clinical Evidence. A number of randomized, controlled trials have evaluated the effectiveness of naltrexone in the management of alcohol dependence with the use of a variety of therapeutic end...
20 Μαΐ 2020 · There are three medications approved for the treatment of alcohol use disorder by the US Food and Drug Administration (FDA): disulfiram, naltrexone (oral and long-acting injectable), and acamprosate.
