Αποτελέσματα Αναζήτησης
13 Δεκ 2001 · Although naltrexone, an opiate-receptor antagonist, has been approved by the Food and Drug Administration for the treatment of alcohol dependence, its efficacy is uncertain.
1 Δεκ 2022 · The article highlights the story of neuroscientist John Sinclair and his discovery that prescribing naltrexone 1 hour before drinking improves drinking outcomes by decreasing the reward of and cravings for alcohol, which may be especially helpful for binge drinkers.
Abstract. The authors examined the efficacy of naltrexone as an adjunctive treatment for alcohol dependence in older adults. Forty-four veterans over 50 years of age were enrolled in a 12-week, double-blind, placebo-controlled efficacy study of naltrexone (the equivalent of 50 mg per day).
12 Δεκ 2018 · Although alcohol consumption generally decreases with advancing age, 9 demographic trends show an increase in alcohol-use disorder among older adults in the United States, 10,11 and 14.5% of...
5 Σεπ 2012 · Consequently, rapid metabolism of naltrexone can lead to poorer treatment outcomes, including reduced time of alcohol absence, increased alcohol craving and higher risk of return to alcohol or dependent alcohol use.
1 Νοε 2001 · Naltrexone-treated subjects consumed alcohol on average 3% fewer days than placebo patients (P < 0.05), and drank 1.0 standard alcoholic drink less per drinking day than placebo-treated subjects (P < 0.05).
Key benefits of naltrexone include reductions in alcohol cravings and decreased relapse to heavy alcohol consumption, although such effects are modest [20,21,22]. However, these benefits may be undermined by poor medication adherence [ 17 , 23 ].
