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The Basic Local Alignment Search Tool (BLAST) finds regions of local similarity between sequences. The program compares nucleotide or protein sequences to sequence databases and calculates the statistical significance of matches.
Here is a web-based interface for NCBI BLAST+ for Mac. This software was originally developed by NCBI for cloud Linux servers and we ported it to Mac. Procedure below is confirmed to work fine on macOS 10.12 Sierra and OS X 10.11 El Capitan.
How to: Download NCBI Software. Starting with the software program of interest... BLAST (aligns nucleotide and protein sequences) NCBI ToolBox (C/C++ source code for NCBI software) CD-Tree (views and edits protein alignments in CD records) Cn3D (3D structure viewer and alignment editor) e-PCR (finds sequence tagged sites in DNA sequences)
Download and install BLAST+. Installers and source code are available from https://ftp.ncbi.nlm.nih.gov/blast/executables/blast+/LATEST/. Download the databases you need, (see database section below), or create your own. Start searching.
In this protocol we introduce the reader to services used to retrieve entry data in various data formats and to access the data in specific fields (e.g. dbfetch), and analysis tool services, for example, sequence similarity search (e.g. FASTA (Pearson et al. 1988; UNIT 3.9) and NCBI BLAST (Altschul et al. 1997; UNIT 3.3)), multiple sequence ...
23 Ιουν 2008 · For users with administrator privileges and machines MacOSX version 10.5 or higher: Download the ncbi-blast-2.2.18+.dmg installer and double click on it. Double click the newly mounted ncbi-blast-2.2.18+ volume, double click on ncbi-blast-2.2.18+.pkg and follow the instructions in the installer.
Download source code and Linux, MacOs, and Windows binaries from https://ftp.ncbi.nlm.nih.gov/blast/executables/magicblast/LATEST.
