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  1. For adults and adolescents with a first clinical episode of genital HSV infection, the WHO STI guideline suggests a standard dose of aciclovir over valaciclovir or famciclovir. Conditional recommendation, moderate quality evidence. Dosages:

  2. 8 Απρ 2024 · Herpes simplex is a viral infection that may cause cold sores around the mouth (oral herpes) or genital herpes. It is caused by the herpes simplex virus type 1 (HSV-1) or type 2 (HSV-2), and spread through contact with herpes lesions, mucosal or genital secretions, or oral secretions. Both HSV-1 and HSV-2 can be passed from normal-looking skin.

  3. 3 Μαρ 2023 · Medication can shorten herpes flare-ups, ease symptoms, and reduce a person’s chance of passing herpes on to other people. As such, doctors typically recommend that a person with herpes get...

  4. 4 Μαρ 2024 · This topic review addresses the treatment of first and repeated episodes of genital herpes simplex infection. The epidemiology, clinical manifestations, and diagnosis of genital HSV infection and issues related to pregnancy are discussed separately.

  5. Pritelivir is extremely active in cell culture and has been shown in two clinical trials to have significant activity against genital HSV infections. To date, therapy has been limited to the short-term treatment of genital herpetic infections as opposed to long-term suppressive therapy.

  6. Acyclovir is the first choice therapeutic agent for HSV infections, including herpes genitalis. However bioavailability is only 15–30 % with oral administration. Infections of the skin and mucous membranes including herpes genitalis are treated orally in immune competent people.

  7. 13 Μαρ 2024 · Despite this, most infection outbreaks will present with nonspecific symptoms such as genital itching, irritation, and excoriations, which may cause diagnosis and treatment to be delayed. As a result, further exposure to uninfected individuals may occur.

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