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17 Αυγ 2022 · Subclinical cerebral edema, as detected by ventricular narrowing on imaging studies or alterations in brain water distribution on magnetic resonance imaging (MRI), has been reported in the majority of children with DKA, even in the absence of neurologic signs or symptoms (image 1) [6,15,16].
This review critically examines the literature on the pathophysiology of CE and attempts to categorize the findings by types of brain injury that contribute to its development: cytotoxic, vasogenic, and osmotic.
Fourth, data suggest that the predominant pathophysiology early after initial cerebral injury (broadly defined) is cerebral ischemia, followed in the subacute stages by a more vasogenic process.
18 Δεκ 2018 · Treatment of cerebral edema in DKA with hyperosmolar agents is recommended as the pathophysiology of cerebral edema is not very well understood.6, 16, 17, 18, 19 An ischemic6 and/or vasogenic18 process is proposed to play a role in the genesis of DKA related cerebral edema.
Cerebral edema (CE) is a potentially devastating complication of diabetic ketoacidosis (DKA) that almost exclusively occurs in children. Since its first description in 1936, numerous risk factors have been identified; however, there continues to be ...
Objective: To review the causes of cerebral edema in diabetic ketoacidosis (CEDKA), including pathophysiology, risk factors, and proposed mechanisms, to review the diagnosis, treatment, and prognosis of CEDKA and the treatment of diabetic ketoacidosis as it pertains to prevention of cerebral edema. Data source: A MEDLINE search using OVID was ...
Cerebral edema during diabetic ketoacidosis (DKA) has been attributed to osmotic cellular swelling during treatment. We evaluated cerebral water distribution and cerebral perfusion during DKA treatment in children.