Αποτελέσματα Αναζήτησης
Objective: Psychotropic drugs often induce weight gain, leading to discomfort and discontinuation of treatment and, more importantly, increasing the risk of obesity-related illnesses such as diabetes mellitus, hypertension, and coronary heart disease.
23 Μαΐ 2018 · While the risk of weight gain without antidepressant use decreased with age and increased with increasing BMI category, the incidence of weight gain was higher for participants treated with antidepressants than for those not treated with antidepressants across all subgroups.
15 Οκτ 2010 · This is the first comprehensive meta-analysis to allow comparison of different antidepressants as regards their impact on body weight and Quantitative results evidenced that amitriptyline, mirtazapine, and paroxetine were associated with a greater risk of weight gain.
When we examined the rate of emergence of significant weight gain—defined as 7% or more increase in body weight—the rate was about 25.5% for paroxetine, significantly higher than the rates for fluoxetine (6.8%) and sertraline (4.2%).
Weight gain is less likely with SSRIs when they are used for 6 months or less. There are diverse opinions about whether increases in body weight occur in patients using them for 1 year or longer. Paroxetine may be more likely than other SSRIs to cause weight gain during short-term or long-term treatment.
2 Αυγ 2024 · The antidepressants led to the following average weight gain: sertraline: Nearly 0.5 pounds at six months; 3.2 pounds at 24 months. escitalopram: 1.4 pounds at six months; 3.6 pounds at 24 months. paroxetine: 1.4 pounds at six months; 2.9 pounds at 24 months.
Methodological quality of studies, heterogeneity, publication bias, and effect of treatment duration were systematically controlled. Data synthesis: Quantitative results evidenced that amitriptyline, mirtazapine, and paroxetine were associated with a greater risk of weight gain.
