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PET imaging provides substantial insights into the pathophysiology of schizophrenia. Although this imaging technique involves exposure to ionizing radiation and is expensive, compared with MRI, it is particularly valuable in understanding the neurobiological mechanisms underpinning schizophrenia.
14 Νοε 2022 · Cannabinoid receptor binding PET agents have been applied to patients with schizophrenia based on the observation that cannabis may be associated with acute psychoses and its use appears to be a risk factor for schizophrenia.
1 Απρ 2018 · The diagnosis of schizophrenia is usually performed clinically by an operational approach such as implemented in the two most widespread diagnostic systems ICD-10 and DSM-V. Schizophrenic disorder is primarily characterized by so-called “positive symptoms” such as delusions, hallucinations and thought disturbances, and “negative symptoms ...
PET is an important functional imaging technique that can be used to investigate neurotransmitter receptors and transporters directly by mapping human brain function. PET is increasingly being used greatly to advance our understanding of the neurobiology and pathophysiology of schizophrenia.
PET is an important functional imaging technique that can be used to investigate neurotransmitter receptors and transporters directly by mapping human brain function.
2 Οκτ 2021 · PET imaging biomarkers have great promise as diagnostic, prognostic, and predictive markers for psychosis. At present, biomarkers with the greatest possible clinical utility have centred around measuring neuroinflammation, dopaminergic dysfunction, and the α7-nAChR receptor density.
19 Απρ 2016 · A common analytical approach in positron emission tomography (PET) imaging is to statistically compare a patient’s PET images on a voxel-by voxel basis to a database of healthy individuals matched for age and gender (normative database).
