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10 Δεκ 2021 · For infants and children with benign etiologies, including primary autoimmune neutropenia due to the development of antineutrophil autoantibodies, symptoms are usually lacking, and the discovery of neutropenia is incidental.
- Autoimmune and other acquired neutropenias | Hematology, ASH Education ...
This educational review addresses the diagnostic evaluation...
- How we evaluate and treat neutropenia in adults
Primary autoimmune neutropenia usually occurs during the...
- Autoimmune and other acquired neutropenias | Hematology, ASH Education ...
2 Δεκ 2016 · This educational review addresses the diagnostic evaluation of patients for autoimmune and other forms of acquired neutropenia, including the futility of deconstructing the overlap of chronic “autoimmune,” “benign,” and “idiopathic” categories.
Primary autoimmune neutropenia primarily affects infants and toddlers. It involves having a low neutrophil count that can’t be explained by other causes. Primary neutropenia usually resolves on its own within a few years. Secondary autoimmune neutropenia is more common in older children and adults.
27 Απρ 2023 · Five main topics were identified: (1) definition and classification of neutropenias, (2) diagnostic approach, (3) natural history and follow-up, (4) treatment, and (5) special situations, and a number of key questions were formulated for each topic.
21 Αυγ 2014 · Primary autoimmune neutropenia usually occurs during the first year of life. As the name implies, it manifests without other signs or symptoms of an underlying autoimmune disorder. 46 Neutropenia can be moderate to severe and complicated by serious infections.
15 Ιαν 2023 · The primary form of AIN is dominant in children, and it presents commonly as a hematologic abnormality and bonemarrow hypoplasia. The secondary form of AIN is present in adults as autoimmune disorders, primary immune deficiencies, infections, hematologic malignancies, or drug exposure.
Autoimmune neutropenias (AIN) are often defined by a reduction of the absolute peripheral blood (PB) neutrophil count (ANC) below the reference values for age 4–7 ( Table 1) together with the demonstration of autoantibodies against human neutrophil antigens (HNAs) ( Figure 1 ). 8–13 In addition to humoral immunity, that is, autoantibodies, cellu...
