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Are you unsure about the procainamide dose for ACLS? Learn about procainamide dosage recommendations, side effects, and more for effective treatment.
3 Σεπ 2024 · ACLS guidelines: Loading dose: Infuse 20 mg/minute (up to 50 mg/minute for more urgent situations) until arrhythmia is controlled, hypotension occurs, QRS complex widens by 50% of its original width, or total of 17 mg/kg is given.
Adult Dosage for Procainamide: The use of procainamide is limited in ACLS for cardiac arrest, due to its requirement of slow infusion and its somewhat unknown effectiveness. If used for recurrent ventricular fibrillation and pulseless ventricular tachycardia, 20 mg/min should be given via IV infusion to a total dose of 17 mg/kg.
8 Μαΐ 2023 · Procainamide is given IV or PO with the onset of action in 10 to 30 minutes. The loading dose is of IV procainamide is 10 to 17 mg/kg and administered at a rate of 20 to 50 mg/min. Alternatively, this may be dosed at 100 mg every 5 minutes in adult patients.
The mean dose of procainamide was 1207 ± 487 mg/day. Procainamide therapy significantly decreased ICD interventions (median 5 [0–22.5] vs 15.5 [3–32.25], P < .05). Procainamide also decreased the total number of VT/VF episodes (median 5.5 [0.75–30] vs 19 [7.5–30], P < .05). Only 3 patients (8.8%) presented severe side effects (dyspnea ...
The maximum advisable dosage to be given either by repeated bolus injections or such loading infusion is 1 g. To maintain therapeutic levels, a more dilute intravenous infusion at a concentration of 2 mg/mL is convenient (1000 mg procainamide HCl in 500 mL of 5% Dextrose Injection, USP), and may be administered at 1 to 3 mL/minute.
10 Φεβ 2020 · Although manufacturer's labeling suggests a maximum total loading dose of 1 g, clinical evidence suggests higher weight-based loading doses of up to 17 mg/kg may be needed (ACLS [Neumar 2010]). Maintenance infusion: 1 to 4 mg/minute (ACLS [Neumar 2010]; Hazinski 2015).
