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SIM is a program which finds a user-defined number of best non-intersecting alignments between two protein sequences or within a sequence [more]. Once the alignment is computed, you can view it using LALNVIEW, a graphical viewer program for pairwise alignments [reference to LANVIEW].
- Sim
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- Sim
Multiple sequence alignment in high-quality scientific databases and software tools using Expasy, the Swiss Bioinformatics Resource Portal.
Building a homology model comprises four main steps: (i) identification of structural template (s), (ii) alignment of target sequence and template structure (s), (iii) model-building, and (iv) model quality evaluation. These steps require specialised software and integrate up-to-date protein sequence and structure databases.
Protein sequence alignment and ExPASy Tools Objective: • To know how to use BLSTP, and find similarities between protein sequences. • To know how to use Clustal W/Omega, and find similarities between multible sequences. • Translation of a nucleotide sequence to a protein sequence using ExPASy.
Multiple Sequence Alignment (MSA) is a way of arranging three or more biological sequences (protein or nucleic acid) to identify regions of similarity that may be a consequence of functional or structural relationships between the sequences.
1 Ιουλ 2003 · SWISS-PROT, PROSITE, ENZYME and SWISS-2DPAGE are updated at a frequency of ∼1–2 weeks. For all the ExPASy databases, data and associated documentation files can be copied locally by anonymous FTP (ftp.expasy.org).
The ExPASy protein identification and characterization tools, in particular Aldente, FindMod, GlycoMod, and FindPept, are closely integrated and hyperlinked with Swiss- Prot and TrEMBL entries on ExPASy, and among each other.