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11 Νοε 2014 · The RNA World concept is the idea that billions of years ago — before current life based on DNA, RNA and proteins — the primary living substance was RNA or something chemically similar.
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1 Δεκ 2023 · This is often understood as the further evolution in the RNA World towards the RNA-protein World. It is a path towards the emergence of translation and the genetic code (I), signaling pathways with signaling molecules (II), and the appearance of RNA-based components of future gene regulatory networks (III).
The RNA World and the Origins of Life. To fully understand the processes occurring in present-day living cells, we need to consider how they arose in evolution.
The RNA world is a hypothetical stage in the evolutionary history of life on Earth in which self-replicating RNA molecules proliferated before the evolution of DNA and proteins. [1] The term also refers to the hypothesis that posits the existence of this stage.
5 Οκτ 2015 · The RNA World is a proposed primitive biochemistry dominated genetically and functionally by RNA (Figure 1). Its existence was proposed in the 1960s [3–5], based on the centrality of RNA and RNA-like cofactors in modern metabolism, as well as the observation that RNA could fold into complex three-dimensional structures reminiscent of proteins.
The RNA world. Biologists used to view RNA as a lowly messenger — the molecule that carries information from DNA to the protein-building centers of the cell. But discoveries since the early 1980s have shown that RNA can do much more.
Though the proportion of the contemporary RNA World that derives from the ancient RNA World remains uncertain, it is clear that much of life's nonuniversal RNA architecture represents newer evolutionary additions to different lineages.
