Αποτελέσματα Αναζήτησης
25 Οκτ 2014 · Increasing the knowledge on the way in which signaling circuits operate is crucial: changes in the activity of the biological functions triggered by signaling pathways (via the circuits that compose them) are behind the mechanisms of several diseases.
11 Ιουν 2018 · Pathways represent spatial and temporal sets of context-dependent interactions, generating a high-level network when linked together, which incorporates contextual information without the need...
Detailed mechanisms for the elimination of intracellular microorganisms involve controlling inflammation through regulatory interactions with innate immune signaling pathways, by removing endogenous inflammasome agonists and through effects on the secretion of immune mediators 138.
31 Οκτ 2019 · Here, we designed a web knowledgebase, the Signaling Pathways Project (SPP), which incorporates community classifications of signaling pathway nodes (receptors, enzymes, transcription...
3 Ιαν 2022 · First, this article reviews non-tumour diseases and conditions related to the Wnt/β-catenin signalling pathway, such as hair loss, pigment disorders, wound healing, bone diseases,...
1 Ιουλ 2013 · Our model, SDREM, integrates static and time series data to link proteins and the pathways they regulate in these networks. SDREM uses prior information about proteins’ likelihood of involvement in a disease (e.g. from screens) to improve the quality of the predicted signaling pathways.
20 Φεβ 2008 · While SPIKE's modeling scheme can accommodate data on any signaling pathway from any organism, at present the implemented DB supports data obtained only in human cells (as genes are associated with the human Entrez-Gene ID and are designated using their HGNC official symbol).
