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16 Ιουν 2023 · Clinical manifestations – Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease with a wide range of clinical and serologic manifestations that can affect virtually any organ. The disease course is often marked by remissions and relapses and may vary from mild to severe.
- Daniel J Wallace, MD
Section Editor — Systemic Lupus Erythematosus Professor of...
- Benito-Garcia E, Schur Ph, Lahita R, American College of Rheumatology Ad Hoc Committee on Immunologic Testing Guidelines. Guidelines for Immunologic Laboratory Testing in The Rheumatic Diseases: anti-Sm and anti-RNP Antibody Tests. Arthritis Rheum 2004; 51:1030
Medline ® Abstract for Reference 52 of 'Clinical...
- Guidelines for Referral and Management of Systemic Lupus Erythematosus in Adults. American College of Rheumatology Ad Hoc Committee on Systemic Lupus Erythematosus Guidelines. Arthritis Rheum 1999; 42:1785
Systemic lupus erythematosus (SLE) is a multiorgan disease...
- Ehmke Ta, Cherian Jj, Wu Es, Et Al. Treatment of Osteonecrosis in Systemic Lupus Erythematosus: a Review. Curr Rheumatol Rep 2014; 16:441
The pathogenesis of ON is largely unknown; however, there...
- Aringer M, Costenbader K, Daikh D, Et Al. 2019 European League Against Rheumatism/American College of Rheumatology Classification Criteria for Systemic Lupus Erythematosus. Arthritis Rheumatol 2019; 71:1400
In the validation cohort, the new criteria had a sensitivity...
- Gladman Dd, Hussain F, Ibañez D, Urowitz Mb. The Nature and Outcome of Infection in Systemic Lupus Erythematosus. Lupus 2002; 11:234
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- Nived O, Sturfelt G, Wollheim F. Systemic Lupus Erythematosus and Infection: a Controlled and Prospective Study Including an Epidemiological Group. Q J Med 1985; 55:271
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- Daniel J Wallace, MD
4 Αυγ 2023 · Objectives: Identify when to consider systemic lupus erythematosus on the differential diagnosis. Describe the evaluation of systemic lupus erythematosus. Explain the treatment options for systemic lupus erythematosus.
Systemic lupus erythematosus (SLE) is a multisystem chronic autoimmune disease with a relapsing and remitting course. Its prevalence is higher in women of childbearing age, with a female predominance of 9:1 . The exact etiology of this disease is not understood well.
6 Οκτ 2017 · SLE (or lupus for short) is a multisystem, autoimmune disease, involving complex pathogenetic mechanisms that can present at any age. It most commonly presents in women in the reproductive age group, although lupus is increasingly recognized after the age of 40 years, particularly in Europeans [1–3].
Systemic lupus erythematous (SLE) is a chronic autoimmune inflammatory disease characterized by autoantibodies directed against numerous self-nuclear antigens. Due to the heterogeneous nature of lupus, it has been challenging to identify markers that are sensitive and specific enough for its diagnosis and monitoring.
21 Οκτ 2022 · Laboratory tests. Blood and urine tests may include: Complete blood count. This test measures the number of red blood cells, white blood cells and platelets as well as the amount of hemoglobin, a protein in red blood cells. Results may indicate you have anemia, which commonly occurs in lupus.
5 Δεκ 2020 · Positive ANA is required for SLE classification and ANA remains an appropriate screening test. While SLE manifestations are extremely variable, the 24 items in 10 domains will classify most patients. For classification and diagnosis, symptoms should only count when there is no more likely alternative explanation.