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4 Αυγ 2023 · Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with multisystemic involvement. The condition has several phenotypes, with varying clinical presentations from mild mucocutaneous manifestations to multiorgan and severe central nervous system involvement.
Systemic lupus erythematosus (SLE) is an autoimmune disease characterised by the loss of self-tolerance and formation of nuclear autoantigens and immune complexes resulting in inflammation of multiple organs.
Objectives To analyse the new evidence (2018–2022) for the management of systemic lupus erythematosus (SLE) to inform the 2023 update of the European League Against Rheumatism (EULAR) recommendations. Methods Systematic literature reviews were performed in the Medline and the Cochrane Library databases capturing publications from 1 January 2018 through 31 December 2022, according to the ...
1 Ιαν 2021 · A Review of Systemic Lupus Erythematosus (SLE): Symptoms, Risk Factors, Treatment, and Health Related Quality of Life Issues. January 2021. Open Journal of Rheumatology and Autoimmune...
Systemic lupus erythematosus (SLE) is a chronic systemic autoimmune disease of variable severity and course, characterised by a tendency for flare (figure 1).1 In SLE, both innate and adaptive immune responses are involved.
17 Απρ 2024 · Systemic lupus erythematosus (SLE) is a multisystemic autoimmune disease, characterised by the presence of autoantibodies towards nuclear antigens, immune complex deposition, and chronic inflammation at classic target organs, such as skin, joints, and kidneys.
A recently proposed system categorised symptoms of SLE in two types: the typical inflammatory symptoms (‘type 1’) requiring immunosuppression, and symptoms such as those mentioned above (‘type 2’), which do not respond to immunosuppressive therapy, yet often dominate patient-reported outcomes.117 We acknowledge that the current ...
