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If we eat sugar on a regular basis, the chemicals build up in our bodies affecting our liver and some other internal organs, which can eventually lead to liver damage. When the liver is damaged, fatty or inflamed, it can’t work as efficiently as a healthy liver.
This review aims to discuss the role of dietary sugar in NAFLD pathogenesis, the health and economic burden, and the promising potential of sugar reduction to improve health outcomes for patients with this chronic liver disease.
8 Ιουν 2022 · This review describes the relationship between DM and non-alcoholic fatty liver disease, the pathophysiological rationale behind this relationship, and its clinical relevance and outcomes. Figure 1 reflects the main mechanisms involved in the physiopathology of NAFLD in different types of diabetes. Figure 1.
In this narrative review, we have addressed several key issues around this debate and the major health conditions previously associated with sugar. We aim to determine the current evidence regarding the role of free sugars in human health, specifically obesity, diabetes, cardiovascular diseases, cognition, and mood.
In summary, there has been a marked rise in sugar and HFCS intake that has paralleled the rise of NAFLD. Experimentally, the fructose component of sugar and HFCS appears to have a major role in inducing fatty liver by both stimulating de novo lipogenesis and blocking β-fatty acid oxidation.
Ingestion of fructose chronically has contributed to multiple health consequences, such as insulin resistance, obesity, liver disorders, and diabetes. Fructose metabolism starts with fructose phosphorylation by fructose kinase in the liver, and this process is not feedback regulated.
3 Μαρ 2020 · The World Health Organization has advised reduction of sugar intake to avoid chronic diseases such as fatty liver disease, T2DM, and metabolic disorders.36,37 Despite great concern about the metabolic risks of added sugar, consumption of SSBs is steadily increasing, especially among younger people.4 In addition, people tend to consume diverse ...
