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Learn how alcohol can cause thiamine deficiency, a condition that affects the heart, nerves and brain. Find out the symptoms, risks and treatments of thiamine deficiency and its complications such as beriberi and Wernicke-Korsakoff syndrome.
4 Απρ 2022 · Wernicke-Korsakoff syndrome is a brain and memory disorder due to thiamine deficiency, often caused by alcohol use disorder. Learn about the symptoms, diagnosis, treatment and prevention of this condition.
A deficiency in the essential nutrient thiamine resulting from chronic alcohol consumption is one factor underlying alcohol-induced brain damage. Thiamine is a helper molecule (i.e., a cofactor) required by three enzymes involved in two pathways of carbohydrate metabolism.
1 Ιαν 2016 · Alleviation of thiamine deficiency in alcoholism has been shown to reduce alcohol consumption, and positively impact psychiatric outcomes that may facilitate recovery, particularly in severe cases, and holds promise to reduce suffering associated with this menacing global public health problem.
18 Μαρ 2023 · This study compares two regimens of thiamine substitution (TS) on thiamine blood levels and cognitive function in patients with alcohol use disorder (AUD). It finds that TS is associated with improving cognitive function, especially memory, in AUD patients.
In alcoholic subjects, changes in thiamin supply combined with impaired epithelial thiamin transport and increased metabolic demand are likely the major factors contributing to alcohol-related brain damage.
18 Νοε 2004 · Severe thiamine deficiency (TD) may result in the development of Wernicke's encephalopathy (WE).
