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2 Οκτ 2024 · We identify seven previously unknown drug interactions of SLC19A3 and present structures of the transporter in complex with the inhibitors fedratinib, amprolium and hydroxychloroquine.
This thesis aims at investigating the interaction energies between two thymine molecules at different geometries, discussing select wave function based approaches for finding interaction energies, and looking closer at the photochemical dimerisation of two thymine molecules in DNA.
16 Απρ 2009 · Thymine, one of the four ubiquitous DNA bases, is synthesized by the enzyme thymidylate synthase, which catalyses the methylation of the uracil moiety of 2′-deoxyuridine-5′-monophosphate.
Experimental and theoretical study of thymine and cytosine derivatives: the crucial role of weak noncovalent interactions. Elies Molins. 2012, CrystEngComm. See full PDF. download Download PDF. Mass Spectrometry and Theoretical Studies on N–C Bond Cleavages in the N-Sulfonylamidino Thymine Derivatives.
1 Φεβ 2005 · The improved knowledge of the complex mechanism of the biological pathways in which thymidylate synthase is involved represents a unique chance to find new mechanism-based inhibitors, aimed to...
9 Φεβ 2021 · In the present study, the dissociation of thymine to thymine dimers and (6-4) photoproducts was detected by means of a Raman, absorption, and synchronous fluorescence study.
We report a simple, selective and cost effective method for the qualitative and quantitative determination of thymine in a DNA standard and urine samples using gold nanoparticles (AuNPs) as a label-free colorimetric biochemical sensor.
