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TIBC is primarily used to calculate transferrin saturation, a more informative indicator of iron availability. Expected Values. Normal Range: TIBC levels typically range between 250-450 mcg/dL (45-81 μmol/L). Importance in Iron Studies Interpretation. Elevated TIBC: Often observed in iron deficiency. The body increases transferrin production ...
The total iron binding capacity (TIBC) reflects the available iron binding sites on transferrin. It requires the measurement of serum iron and transferrin that is not bound to iron (i.e., the unbound iron binding capacity, UIBC). The TIBC is the sum of serum iron and the UIBC.
Total iron-binding capacity (TIBC) or sometimes transferrin iron-binding capacity is a medical laboratory test that measures the blood's capacity to bind iron with transferrin. [1] . Transferrin can bind two atoms of ferric iron (Fe 3+) with high affinity.
15 Δεκ 2022 · Total iron-binding capacity (TIBC) measures the total capacity of your blood to bind and transport iron. It is used to estimate the amount of iron stored in your body [ 1 , 2 ]. TIBC is an indirect measure of transferrin , a protein that binds iron molecules and transports them in the bloodstream.
Serum iron is reported to drop with acute infarct of myocardium. TIBC is increased in iron-deficiency, use of oral contraceptives, and in pregnancy. TIBC is decreased in hypoproteinemia due to many causes, and is decreased in a number of inflammatory states.
This concise lab report format delves into the key aspects of the TIBC test, including its purpose, sample type, normal values, and significance in guiding healthcare professionals in the assessment and treatment of individuals with iron-related issues.
A TIBC (total iron-binding capacity) test is a blood test that measures your blood’s ability (capacity) to attach (bind) to iron and carry it throughout your body. Healthcare providers use it to help diagnose iron-deficiency anemia and other iron metabolism conditions.