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  1. 1 Ιουλ 2023 · The TiO 2 NPs have been used in drug delivery and combined cancer treatments due to their ability to reach drug release in cancer cells, their autophagic, photodynamic characteristics, and their non-toxicity up to a concentration of 1 μg mL −1 for normal cells.

  2. It has been reported that the elevated level of oxidative stress by exogenous agents, due to the elevation of ROS in tumor environment, can be more destructive in cancer cells. 41 Prior studies have shown that induction of ROS production in a tumor environment triggers apoptosis, which is the appropriate type of cell death in cancers. 42 Thus ...

  3. 26 Ιαν 2021 · Hydroxyl radicals (OH) are associated with titanium dioxide (TiO2) nanoparticle-induced cytotoxicity and oxidative DNA damage in fish cells. Mutation Research, Fundamental and Molecular Mechanisms of Mutagenesis.

  4. 4 Νοε 2021 · In this work, we systematically studied the interactions between three sizes of TiO 2 particles and the cell membrane systems with confocal laser scanning microscopy. We used both giant unilamellar vesicles and human colon cancer cells to mimic actual cell membrane systems.

  5. These materials have also been used to kill bacteria in water treatment 191 and tumor cells in cancer treatment. 14,192 Some reviews are available on the photocatalytic mechanisms. 11,16,24,33 By the absorption of photon hv 1, the photocatalytic mechanism is initiated manufacturing an electron–hole pair on the surface of TiO 2 nanoparticle ...

  6. 15 Οκτ 2022 · Nanoparticulate TiO 2 (TiO 2 NPs) is a widely used material, whose potential toxicity towards eukaryotic cells has been addressed by multiple studies. TiO 2 NPs are considered toxic due to their production of reactive oxygen species (ROS), which can, among others, lead to cellular damage, inflammatory responses, and differences in gene expression.

  7. 2 Σεπ 2022 · We performed a 26-week inhalation exposure studies of titanium dioxide nanoparticles (TiO2 NPs) using CByB6F1-Tg(HRAS)2Jic (rasH2) mice model for detecting carcinogenicity.