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Here, we discuss the emerging promise of nanotechnology in vaccine design and manufacturing to combat SARS-CoV-2, and highlight opportunities and challenges presented by these novel vaccine platforms.
2 Σεπ 2021 · The SARS-CoV-2 pandemic has heralded a coming-of-age for vaccine nanotechnology. Decades of groundwork optimizing new vaccine platforms allowed clinical trials with nanoparticle vaccine candidates to begin within 2 months of the SARS-CoV-2 genome sequence being made publicly available.
15 Απρ 2013 · Titanium dioxide (TiO2) nanoparticles (NPs) are manufactured worldwide in large quantities for use in a wide range of applications. TiO2 NPs possess different physicochemical properties compared to their fine particle (FP) analogs, which might alter their bioactivity.
7 Ιουλ 2022 · The current study investigates the effectiveness of said TiO 2 nanostructured surfaces against two enveloped human coronaviruses, SARS-CoV-2 and HCoV-NL63, and nonenveloped HRV-16 for surface-based inactivation.
26 Ιαν 2021 · Hydroxyl radicals (OH) are associated with titanium dioxide (TiO2) nanoparticle-induced cytotoxicity and oxidative DNA damage in fish cells. Mutation Research, Fundamental and Molecular Mechanisms of Mutagenesis.
16 Ιουν 2022 · Several vaccines against COVID-19 use nanoparticles to protect the antigen cargo (either proteins or nucleic acids), increase the immunogenicity and ultimately the efficacy.
27 Νοε 2020 · Two nanoparticle-based vaccines close to obtaining approval by the US Food and Drug Administration could represent a giant step in the fight against the COVID-19 pandemic. On 18 November...