Αποτελέσματα Αναζήτησης
1 Δεκ 2010 · Uracil may arise in DNA as a result of spontaneous cytosine deamination and/or misincorporation of dUMP during DNA replication.
- DNA-uracil and Human Pathology
The discovery of uracil-DNA glycosylase in Escherichia coli...
- DNA-uracil and Human Pathology
16 Δεκ 2002 · UNG2 is a major nuclear uracil-DNA glycosylase central in removal of misincorporated dUMP in replication foci, but recent evidence also indicates an important role in repair of U : G mispairs and...
10 Αυγ 2020 · Uracil may arise in DNA as a result of spontaneous cytosine deamination and/or misincorporation of dUMP during DNA replication. In this paper we will review: (i) sources of the origin of uracil in DNA; (ii) some properties of the enzymes responsible for the excision of uracil and their role in the I ….
6 Ιουν 2024 · In the absence of uracil DNA glycosylase (UNG), genomic uracil accumulates to high levels, DNA replication forks slow down, and PrimPol-mediated repriming is enhanced, generating single-stranded gaps in nascent DNA.
6 Ιουν 2024 · In the absence of uracil DNA glycosylase (UNG), genomic uracil accumulates to high levels, DNA replication forks slow down, and PrimPol-mediated repriming is enhanced, generating single-stranded gaps in nascent DNA.
1 Ιουν 2007 · The discovery of uracil-DNA glycosylase in Escherichia coli and subsequently other DNA glycosylases revealed that repair of small base lesions by the process called base excision repair (BER) is a universal DNA repair pathway found in prokaryotes and eukaryotes.
patch pathway, which largely use different proteins. UNG2 is a major nuclear uracil-DNA glycosylase central in removal of misincorporated dUMP in replication foci, but recent evidence also...
