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9 Απρ 2018 · Preliminary studies in humans and animals suggest that getting adequate amounts of vitamin K might help to slow the progression of osteoarthritis—a common condition marked by breakdown of joint cartilage and associated inflammation and disability. An estimated 30 million Americans have osteoarthritis.
12 Απρ 2021 · Vitamin K is important for healthy functioning of proteins in cartilage and bone, two major tissues in joints that are affected in osteoarthritis. For example, a protein called matrix Gla protein (MGP) depends on vitamin K to help prevent cartilage calcification.
Vitamin K and osteoarthritis: is there a link? Ann Rheum Dis. 2021 May;80 (5):547-549. doi: 10.1136/annrheumdis-2020-219765. Epub 2021 Apr 12. Authors. Richard F Loeser 1 , Francis Berenbaum 2 , Margreet Kloppenburg 3. Affiliations.
Objectives: Vitamin K has bone and cartilage effects, and previously shown to be associated with radiographic osteoarthritis. We evaluated vitamin K's effect on hand osteoarthritis in a randomised controlled trial. Methods:
Vitamin K antagonists function by inhibiting VKORC1 and thus decrease the amount of reduced vitamin K and, in turn, the production of functional Gla-containing VKDPs. These include specific coagulation proteins but also
24 Ιουλ 2024 · These 20 vitamins and supplements for arthritis are proven to relieve pain and inflammation, prevent disease progression, and improve overall health.
25 Απρ 2020 · This review collates the evidence on the relationship between vitamin K status (circulating or dietary intake level of vitamin K, or circulating uncarboxylated gla proteins) and OA from human observational studies and clinical trial, to examine its potential as an agent in preventing OA.