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A conjugate vaccine is a type of subunit vaccine which combines a weak antigen with a strong antigen as a carrier so that the immune system has a stronger response to the weak antigen. Vaccines are used to prevent diseases by invoking an immune response to an antigen, part of a bacterium or virus that the immune system recognizes. [2]
Subunit vaccines are made from a piece of a pathogen, not the whole organism, so they do not contain any live pathogens. Some important subunit vaccines are polysaccharide vaccines, conjugate vaccines, and protein-based vaccines.
Conjugate vaccines are the most effective form of immunization for those under two years of age who are particularly vulnerable to bacterial meningitis. High-income countries have reported an increase in invasive pneumococcal disease from non-vaccine serotypes with the introduction of conjugate vaccines.
30 Απρ 2021 · Adjuvants are often added to subunit vaccines. These are substances which help to strengthen and lengthen the immune response to the vaccine. As a result, common local reactions (such as a sore arm) may be more noticeable and frequent with these types of vaccines.
A conjugate vaccine is a therapeutic agent designed to stimulate the immune system to recognize and attack a potential pathogen invader or a diseased cell. Conjugate vaccines can also be used to generate protective IgG antibodies against allergy-related antigens to prevent the binding of IgE and modulate an allergic reaction.
22 Δεκ 2020 · However, converting plain polysaccharide vaccines into T cell-dependent protein–polysaccharide conjugate vaccines, which are immunogenic from 2 months of age and induce immune memory, has ...
28 Σεπ 2020 · A new typhoid conjugate vaccine, consisting of Vi conjugated to tetanus toxoid (Typbar TCV), has shown promising immunogenicity and safety results in clinical trials.
