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10 Ιαν 2022 · Two cannabinoids with the highest affinities for the spike protein, cannabidiolic acid (CBDA) and cannabigerolic acid (CBGA), were confirmed to block infection of human epithelial cells by a pseudovirus expressing the spike protein.
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cells.14,15 The approach of utilizing compounds that block...
- MagMASS
To expedite the identification of active natural products in...
- Journal of Natural Products
This contribution is a completely updated and expanded...
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Cannabis and its active cannabinoids act as immune-modulating agents, affecting T-cells, B-cells, monocytes, and microglia, causing an overall reduction in proinflammatory cytokine expression and an increase in anti-inflammatory cytokines.
29 Δεκ 2020 · When it comes to pathogenic bacterial infections, it has been shown that exogenous cannabinoids, especially THC, can reduce resistance to bacterial infections like Listeria monocytogenes, Treponema pallidum, Legionella pneumophila, Staphylococci aureus, and S. albus in animal models suggesting the same outcome in humans .
15 Μαρ 2021 · In C. sativa, cannabinoids are biosynthesized as phytoprotectants: in fresh biomass, 95% of the THC, CBD, and CBC exist as their acidic parents: tetrahydrocannabinolic acid (THCA), cannabidiolic acid (CBDA), and cannabichromenic acid (CBCA) (United Nations Office on Drugs and Crime 2005).
Key examples of arachidonic acid-based cannabinoids include anandamide (1), 2-arachidonylglycerol (2-AG) (2, 3), and virodhamine (12). Rapidly produced from lipid precursors, these eicosanoids are released in response to neuronal activity and pro-inflammatory agents (13).
Cannabinoid is a term that designates compounds of the Cannabis sativa plant. The main psychoactive compounds are Δ 9 -tetrahydrocannabinol (Δ 9 -THC) and cannabidiol (CBD), which may produce opposite effects on human brain function (Bhattacharyya et al., 2010).
22 Ιαν 2019 · In addition to plant cannabis sativa, there are two classes of cannabinoids—the synthetic cannabinoids (e.g., WIN55212–2) and the endogenous cannabinoids (eCB), anandamide (ANA) and 2 ...
