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Research into basic mechanisms underlying pain is an increasingly exciting and promising area. However, most of what is known about the anatomy and physiology of pain is from studies of experimentally induced cutaneous (skin) pain, while most clinical pain arises from deep tissues.
There are three types of pain classified by cause. The pain you feel when you stub your toe or put your hand on a hot pan is called nociceptive pain. A sensory neuron—or nociceptor—transmits an electrical impulse to the spinal cord and then to the brain, where it is experienced as pain.
24 Ιουλ 2023 · Nociceptive signal transduction to the brain is what elicits the perception of pain. The complex biopsychosocial phenomenon of pain occurs in the cortical and subcortical regions, such as the thalamus, amygdala, hypothalamus, periaqueductal grey, basal ganglia and areas of the cerebral cortex.
Pain is a vital physiological function that has evolved to alert the individual to the presence of noxious stimuli, minimising the risk of tissue damage and protecting against ongoing tissue injury. However, uncontrolled or inappropriate pain may have negative and far-reaching consequences.
17 Απρ 2023 · An individual’s capacity to feel pain is an essential component of the body’s ability to heal. Pain is the body’s way of telling us there is an injury, and we need to do something about it to ensure that healing occurs.
1 Οκτ 2022 · This article gives a broad overview of the anatomy and physiology of pain. The normal pain pathways are described in some detail in a systematic fashion from nociceptor to central nervous system and back to periphery.
Pain as experienced as an unpleasant sensory and emotional experience is influenced by biological, psychological and social factors – all of which have a physiologic basis. The perception of a painful sensation is founded on the complex integration of nervous system signaling at three levels: Transduction, Transmission and Perception.
