Αποτελέσματα Αναζήτησης
Uracil is well known as one of the bases used in RNA, but why is it not used in DNA – or is it? Angéla Békési and Beáta G Vértessy investigate. Endopterygotes such as ants lack the enzyme capable of removing uracil from their DNA. Thymine versus uracil. Our genetic information is stored in the form of DNA, using a four-letter alphabet.
1 Ιαν 2003 · Uracil in DNA results from deamination of cytosine, resulting in mutagenic U : G mispairs, and misincorporation of dUMP, which gives a less harmful U : A pair.
16 Δεκ 2002 · Uracil in DNA results from deamination of cytosine to uracil, creating a premutagenic U : G mispair, or from misincorporation of dUMP instead of dTMP during replication, creating a U : A pair...
1 Δεκ 2010 · In this paper we will review: (i) sources of the origin of uracil in DNA; (ii) some properties of the enzymes responsible for the excision of uracil and their role in the Ig diversification process, which comprises somatic hypermutation and class switch recombination; and (iii) consequences of cytosine deamination in other than the Ig loci, in ...
24 Σεπ 2018 · Chapter 10, RNA contains the pyrimidine uracil in place of thymine; like thymine, uracil pairs with adenine.) Compared to the 20 disparate side chains of amino acids, the four bases are relatively similar-looking. In contrast to side chains, however, they all principally do one thing: pair with a single complementary base. N N NH N H NH 2 O ...
9 Απρ 2021 · In this review, we provide a comprehensive and critical assessment of the repertoire of available methods measuring uracil-containing DNA (U-DNA) in different contexts with a special focus on next-generation sequencing (NGS)-based genome-wide mapping solutions.
1 Δεκ 2010 · The presence of uracil in DNA is deleterious for living organisms including yeast, bacteria, and humans; it can result either from spontaneous or enzymatic deaminations of cytosines or...
