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Biotin (also known as vitamin B 7 or vitamin H) is one of the B vitamins. [1] [2] [3] It is involved in a wide range of metabolic processes, both in humans and in other organisms, primarily related to the utilization of fats, carbohydrates, and amino acids. [4]
26 Σεπ 2024 · Biotin was first identified as a nutritive requirement of yeast. Originally called vitamin H, it was isolated in pure form in 1935; its structure was established in 1942, after it had been shown to be required by animals.
20 Φεβ 2011 · Biotin was the name given to a substance isolated from egg yolk by Kogl and Tonnis in 1936 that was necessary for yeast growth. This substance was discovered to be identical to a growth factor named coenzymes R that was required by legume nodule bacteria.
23 Οκτ 2012 · The identity of vitamin H and biotin was shown in 1940 by a collaboration of György and du Vigneaud. In 1940, Snell developed a yeast assay system for biotin and using this Snell and Williams isolated the protein in egg white that tightly binds biotin and causes ‘egg white injury’ (Eakin et al. 1940). This was named ‘avidin’ because of ...
Biotin was discovered in nutritional experiments that revealed a factor in many foodstuffs that was capable of curing the scaly dermatitis, hair loss, and neurologic signs induced in rats fed dried egg whites. Avidin, a glycoprotein found in egg whites, binds biotin very specifically and tightly (K a = 10 15 mol/L) (1, 2). From an evolutionary ...
The aim was to describe the discovery of niacin, biotin, and pantothenic acid. By the 1920s, it became apparent that 'water-soluble B' (vitamin B) is not a single substance.
Like many vitamins, biotin was "discovered" several times by different people and was given a new name by each of its discoverers. In the 1920s different researchers isolated a growth factor for yeast that some named "bios," and others called "vitamin H".
